Aberrant DNA methylation of cancer-related genes in giant breast fibroadenoma: a case report

INTRODUCTION: Giant fibroadenoma is an uncommon variant of benign breast lesions. Aberrant methylation of CpG islands in promoter regions is known to be involved in the silencing of genes (for example, tumor-suppressor genes) and appears to be an early event in the etiology of breast carcinogenesis....

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Autori principali: Marzese, Diego M, Gago, Francisco E, Orozco, Javier I, Tello, Olga M, Roqué, María, Vargas-Roig, Laura M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Case Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206866/
https://ncbi.nlm.nih.gov/pubmed/22011321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-1947-5-516
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