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High Resolution Melt analysis for mutation screening in PKD1 and PKD2

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder. It is characterized by focal development and progressive enlargement of renal cysts leading to end-stage renal disease. PKD1 and PKD2 have been implicated in ADPKD pathogenesis but genetic...

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Bibliografiske detaljer
Main Authors: Bataille, Stanislas, Berland, Yvon, Fontes, Michel, Burtey, Stéphane
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206831/
https://ncbi.nlm.nih.gov/pubmed/22008521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-12-57
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