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PDZ binding of TARP©-8 controls synaptic transmission, but not synaptic plasticity
Reduction in synaptic transmission and plasticity in mice lacking the hippocampus-enriched AMPAR auxiliary subunit, TARP©-8, could be due to reduction in AMPAR expression or a direct role of ©-8. Here, we generated TARP©-8Δ4 knock-in mice lacking the C-terminal PDZ ligand. We found that synaptic tra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206644/ https://ncbi.nlm.nih.gov/pubmed/22002768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2952 |
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