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Transcriptomic Analysis of Cell-Free Fetal RNA Suggests a Specific Molecular Phenotype in Trisomy 18

BACKGROUND: Trisomy 18 is a common human aneuploidy that is associated with significant perinatal mortality. Unlike the well-characterized “critical region” in trisomy 21 (21q22), there is no corresponding region on chromosome 18 associated with its pathogenesis. The high morbidity and mortality of...

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Detalhes bibliográficos
Main Authors: Koide, Keiko, Slonim, Donna K., Johnson, Kirby L., Tantravahi, Umadevi, Cowan, Janet M., Bianchi, Diana W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206603/
https://ncbi.nlm.nih.gov/pubmed/21152935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0923-3
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