Differentiation of CD8(+) T cells into effector cells is enhanced by physiological range hyperthermia

In this study, we asked whether exposure to different physiologically relevant temperatures (33°C, 37°C, and 39.5°C) could affect subsequent antigen-specific, activation-related events of naive CD8(+) T cells. We observed that temporary exposure of CD62L(hi)CD44(lo) Pmel-1 CD8(+) cells to 39.5°C pri...

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Detalhes bibliográficos
Main Authors: Mace, Thomas A., Zhong, Lingwen, Kilpatrick, Casey, Zynda, Evan, Lee, Chen-Ting, Capitano, Maegan, Minderman, Hans, Repasky, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2011
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206471/
https://ncbi.nlm.nih.gov/pubmed/21873456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0511229
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