Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA(2)-IIA expression in astrocytes and microglia

BACKGROUND: Activation of glial cells, including astrocytes and microglia, has been implicated in the inflammatory responses underlying brain injury and neurodegenerative diseases including Alzheimer's and Parkinson's diseases. Although cultured astrocytes and microglia are capable of resp...

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Bibliographische Detailangaben
Hauptverfasser: Sheng, Wenwen, Zong, Yijia, Mohammad, Arwa, Ajit, Deepa, Cui, Jiankun, Han, Dongdong, Hamilton, Jennifer L, Simonyi, Agnes, Sun, Albert Y, Gu, Zezong, Hong, Jau-Shyong, Weisman, Gary A, Sun, Grace Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206447/
https://ncbi.nlm.nih.gov/pubmed/21943492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-121
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