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Potential for Modulation of the Fas Apoptotic Pathway by Epidermal Growth Factor in Sarcomas

One important mechanism by which cancer cells parasitize their host is by escaping apoptosis. Thus, selectively facilitating apoptosis is a therapeutic mechanism by which oncotherapy may prove highly advantageous. One major apoptotic pathway is mediated by Fas ligand (FasL). The death-inducing signa...

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Detalhes bibliográficos
Main Authors: Joyner, David E., Jones, Kevin B., Lessnick, Stephen L., Schiffman, Joshua D., Randall, R. Lor
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206362/
https://ncbi.nlm.nih.gov/pubmed/22135505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/847409
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