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Design and Application of Microfluidic Systems for In Vitro Pharmacokinetic Evaluation of Drug Candidates

One of the fundamental challenges facing the development of new chemical entities within the pharmaceutical industry is the extrapolation of key in vivo parameters from in vitro cell culture assays and animal studies. Development of microscale devices and screening assays incorporating primary human...

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Bibliographic Details
Main Authors: Maguire, T.J., Novik, E., Chao, P., Barminko, J., Nahmias, Y., Yarmush, M.L., Cheng, K.-C.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206315/
https://ncbi.nlm.nih.gov/pubmed/20166997
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