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Influence of pH on Ca(2+) current and its control of electrical and Ca(2+) signaling in ventricular myocytes
Modulation of L-type Ca(2+) current (I(Ca,L)) by H(+) ions in cardiac myocytes is controversial, with widely discrepant responses reported. The pH sensitivity of I(Ca,L) was investigated (whole cell voltage clamp) while measuring intracellular Ca(2+) (Ca(2+)(i)) or pH(i) (epifluorescence microscopy)...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206307/ https://ncbi.nlm.nih.gov/pubmed/22042988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110658 |
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