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Statins Do Not Significantly Affect Muscle Sympathetic Nerve Activity in Humans with Non-Ischemic Heart Failure: A Double-Blind Placebo Controlled Trial

BACKGROUND: HMG-CoA reductase inhibitors (statins) have been shown to reduce sympathetic nervous system (SNS) activation in experimental heart failure (HF). However, this potential mechanism of action of statins in HF has not been well studied in humans. METHODS AND RESULTS: Twenty-six patients with...

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Detalhes bibliográficos
Main Authors: Horwich, Tamara B., Middlekauff, Holly R., MacLellan, W. Robb, Fonarow, Gregg C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206298/
https://ncbi.nlm.nih.gov/pubmed/22041323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2011.07.008
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