Capsomer Vaccines Protect Mice from Vaginal Challenge with Human Papillomavirus

Capsomers were produced in bacteria as glutathione-S-transferase (GST) fusion proteins with human papillomavirus type 16 L1 lacking the first nine and final 29 residues (GST-HPV16L1Δ) alone or linked with residues 13–47 of HPV18, HPV31 and HPV45 L2 in tandem (GST-HPV16L1Δ-L2x3). Subcutaneous immuniz...

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Detalhes bibliográficos
Main Authors: Wu, Wai-Hong, Gersch, Elizabeth, Kwak, Kihyuck, Jagu, Subhashini, Karanam, Balasubramanyam, Huh, Warner K., Garcea, Robert L., Roden, Richard B. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206079/
https://ncbi.nlm.nih.gov/pubmed/22069498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027141
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