Study of IspH, A Key Enzyme in the Methylerythritol Phosphate Pathway Using Fluoro-substituted Substrate Analogues

[Image: see text] IspH, a [4Fe-4S]-cluster-containing enzyme, catalyzes the reductive dehydroxylation of 4-hydroxy-3-methyl-butenyl diphosphate (HMBPP) to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) in the methylerythritol phosphate pathway. Studies of IspH using fluoro-subst...

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Hlavní autoři: Xiao, Youli, Chang, Wei-chen, Liu, Hung-wen, Liu, Pinghua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205992/
https://ncbi.nlm.nih.gov/pubmed/21981393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol202559r
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