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An Unexpected Observation Concerning the Effect of Anionic Additives on the Retention Behavior of Basic Drugs and Peptides in Reversed-Phase Liquid Chromatography

Anionic species with ion pair forming ability are commonly used to enhance the retention and efficiency of basic analytes in RPLC separations. However, little is known about the interactions between organic mobile phase modifiers and such ion pairing anions. In this work, we measured the magnitude o...

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Autors principals: Wang, Xiaoli, Carr, Peter W.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205948/
https://ncbi.nlm.nih.gov/pubmed/17448482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2007.03.057
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