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Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model

Thrombospondin-1 is one of most important natural angiogenic inhibitors. The three thrombospondin-1 type 1 repeats (3TSR), an anti-angiogenic domain of thrombospondin-1, is a promising novel agent for anti-angiogenic treatment. In the present study, we showed 3TSR was biologically stable at least fo...

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Detalhes bibliográficos
Main Authors: Zhang, Xuefeng, Connolly, Caitlin, Duquette, Mark, Lawler, Jack, Parangi, Sareh
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205930/
https://ncbi.nlm.nih.gov/pubmed/16757110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2006.04.003
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