Characterization of Anti-HIV Activity Mediated by R88-APOBEC3G Mutant Fusion Proteins in CD4(+) T cells, Peripheral Blood Mononuclear Cells, and Macrophages

In this study, we characterized the anti-HIV activities of various R88-APOBEC3G (R88-A3G) mutant fusion proteins in which each A3G mutant was fused with a virus-targeting polypeptide (R14-88, hereafter named R88) derived from HIV-1 Vpr. Our results show that the introduction of the deaminase-defecti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ao, Zhujun, Wang, Xiaoxia, Bello, Alexander, Jayappa, Kallesh Danappa, Yu, Zhe, Fowke, Keith, He, Xinying, Chen, Xi, Li, Junhua, Kobinger, Gary, Yao, Xiaojian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2011
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205798/
https://ncbi.nlm.nih.gov/pubmed/21182427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.012
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