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Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis

Systemic sclerosis is a connective tissue disease characterized by fibrosis of the skin, internal organs, and widespread vasculopathy. Raynaud's phenomenon and digital ulcers are vascular manifestations of this disease and cause significant morbidity. Current treatments are only moderately effe...

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Autors principals: Arefiev, Kait, Fiorentino, David F., Chung, Lorinda
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205679/
https://ncbi.nlm.nih.gov/pubmed/22121371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/201787
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