Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge

Polycomb group (PcG) proteins are required for the epigenetic maintenance of developmental genes in a silent state. Proteins in the Polycomb-repressive complex 1 (PRC1) class of the PcG are conserved from flies to humans and inhibit transcription. One hypothesis for PRC1 mechanism is that it compact...

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Bibliographic Details
Main Authors: Grau, Daniel J., Chapman, Brad A., Garlick, Joe D., Borowsky, Mark, Francis, Nicole J., Kingston, Robert E.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2011
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205590/
https://ncbi.nlm.nih.gov/pubmed/22012622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.17288211
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