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Revisiting the TCA cycle: signaling to tumor formation
A role for mitochondria in tumor formation is suggested by mutations in enzymes of the TCA cycle: isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH) and fumarate hydratase (FH). Although they are all components of the TCA cycle, the resulting clinical presentations do not overlap. Activat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205302/ https://ncbi.nlm.nih.gov/pubmed/21764377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.06.001 |
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