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TYPE 2 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR MODULATES BILE SALT EXPORT PUMP ACTIVITY IN RAT HEPATOCYTES

Bile salt secretion is mediated primarily by the bile salt export pump (Bsep), a transporter on the canalicular membrane of the hepatocyte. However, little is known about the short-term regulation of Bsep activity. Ca(2+) regulates targeting and insertion of transporters in many cell systems, and Ca...

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Detalhes bibliográficos
Main Authors: Kruglov, Emma A., Gautam, Samir, Guerra, Mateus T., Nathanson, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205211/
https://ncbi.nlm.nih.gov/pubmed/21748767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24548
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