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Antigenic, Immunologic and Genetic Characterization of Rough Strains B.abortus RB51, B.melitensis B115 and B.melitensis B18

The lipopolysaccharide (LPS) is considered the major virulent factor in Brucella spp. Several genes have been identified involved in the synthesis of the three LPS components: lipid A, core and O-PS. Usually, Brucella strains devoid of O-PS (rough mutants) are less virulent than the wild type and do...

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Main Authors: Adone, Rosanna, Muscillo, Michele, La Rosa, Giuseppina, Francia, Massimiliano, Tarantino, Michela
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204967/
https://ncbi.nlm.nih.gov/pubmed/22065984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024073
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