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Increased Neutrophil Adenosine A3 Receptor Expression is Associated with Hemorrhagic Shock and Injury Severity in Trauma Patients

Hypertonic saline (HS) has been investigated as an immune modulator following hemorrhagic shock and sepsis. The neutrophil (PMN) response to HS is regulated by the release of ATP, which is converted to adenosine and activates adenosine receptors. Binding to A3 adenosine receptors promotes PMN activa...

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Detalhes bibliográficos
Main Authors: Bulger, Eileen M., Tower, Cindy M., Warner, Keir J., Garland, Tara, Cuschieri, Joseph, Rizoli, Sandro, Rhind, Shawn, Junger, Wolfgang G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204900/
https://ncbi.nlm.nih.gov/pubmed/21841534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318231ee2e
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