Signaling via the prostaglandin E(2) receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia

Stroke is the third leading cause of death in the United States. Fewer than 5% of patients benefit from the only intervention approved to treat stroke. Thus, there is an enormous need to identify new therapeutic targets. The role of inducible cyclooxygenase (COX-2) activity in stroke and other neuro...

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Главные авторы: Liang, Xibin, Lin, Lu, Woodling, Nathaniel S., Wang, Qian, Anacker, Christoph, Pan, Tingting, Merchant, Milton, Andreasson, Katrin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204834/
https://ncbi.nlm.nih.gov/pubmed/21965326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46279
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