SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target

B-cell chronic lymphocytic leukemia (CLL), an incurable leukemia, is characterized by defective apoptosis. We found that the SET oncoprotein, a potent inhibitor of the protein phosphatase 2A (PP2A) tumor suppressor, is overexpressed in primary CLL cells and B-cell non-Hodgkin lymphoma (NHL) cell lin...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Christensen, Dale J., Chen, Youwei, Oddo, Jessica, Matta, Karen M., Neil, Jessica, Davis, Evan D., Volkheimer, Alicia D., Lanasa, Mark C., Friedman, Daphne R., Goodman, Barbara K., Gockerman, Jon P., Diehl, Louis F., de Castro, Carlos M., Moore, Joseph O., Vitek, Michael P., Weinberg, J. Brice
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2011
Gaiak:
Clinical Trials and Observations
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204732/
https://ncbi.nlm.nih.gov/pubmed/21844565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-351072
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