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Complete concordance between glucose-6-phosphate dehydrogenase activity and hypomethylation of 3' CpG clusters: implications for X chromosome dosage compensation.

To explore the molecular basis of X chromosome inactivation, we have examined the human locus for glucose-6-phosphate dehydro-genase (G6PD) in various human tissues. Studies of DNA from males and females and from somatic cell hybrids with active or inactive X chromosomes, show that two remarkably de...

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Detalhes bibliográficos
Main Authors: Wolf, S F, Dintzis, S, Toniolo, D, Persico, G, Lunnen, K D, Axelman, J, Migeon, B R
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC320465/
https://ncbi.nlm.nih.gov/pubmed/6514579
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