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Up-regulation of cyclooxygenase-2-derived prostaglandin E(2) in colon cancer cells resistant to 5-fluorouracil

PURPOSE: It has been suggested that constitutive up-regulation of cyclooxygenase (COX)-2 is associated with resistance to apoptosis, increased angiogenesis, and increased tumor invasiveness in various cancers including colon cancer. There are many factors involved in the resistance to 5-fluorouracil...

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Autors principals: Choi, Cheol Hee, Lee, Tae Bum, Lee, Yeon Ah, Choi, Suk, Kim, Kyung Jong
Format: Artigo
Idioma:Inglês
Publicat: The Korean Surgical Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204563/
https://ncbi.nlm.nih.gov/pubmed/22066110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4174/jkss.2011.81.2.115
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