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Regulating TRAIL Receptor-Induced Cell Death at the Membrane: A Deadly Discussion

The use of TRAIL/APO2L and monoclonal antibodies targeting TRAIL receptors for cancer therapy holds great promise, due to their ability to restore cancer cell sensitivity to apoptosis in association with conventional chemotherapeutic drugs in a large variety of tumors. TRAIL-induced cell death is ti...

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Bibliographic Details
Main Authors: Shirley, Sarah, Morizot, Alexandre, Micheau, Olivier
Format: Artigo
Language:Inglês
Published: Bentham Science Publishers 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204462/
https://ncbi.nlm.nih.gov/pubmed/21756247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157489211796957757
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