Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock

In animals, circadian oscillators are based on a transcription-translation circuit that revolves around the transcription factors CLOCK and BMAL1. We found that the JumonjiC (JmjC) and ARID domain-containing histone lysine demethylase 1a (JARID1a) formed a complex with CLOCK-BMAL1, which was recruit...

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Bibliographic Details
Main Authors: DiTacchio, Luciano, Le, Hiep D., Vollmers, Christopher, Hatori, Megumi, Witcher, Michael, Secombe, Julie, Panda, Satchidananda
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204309/
https://ncbi.nlm.nih.gov/pubmed/21960634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1206022
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