Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts

BACKGROUND: The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites. Altered levels of KP-metabolites have been observed in neuropsychiatric and neurodegenerative disorders as well as in patients wit...

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Detalhes bibliográficos
Main Authors: Asp, Linnéa, Johansson, Anne-Sofie, Mann, Amandeep, Owe-Larsson, Björn, Urbanska, Ewa M, Kocki, Tomasz, Kegel, Magdalena, Engberg, Göran, Lundkvist, Gabriella BS, Karlsson, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204223/
https://ncbi.nlm.nih.gov/pubmed/21982155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-8-25
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