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IL-27 Inhibits Hyperglycemia and Pancreatic Islet Inflammation Induced by Streptozotocin in Mice
Inflammation driven by immune cells and pro-inflammatory cytokines is implicated in pancreatic β-cell injury, leading to the development of diabetes mellitus. IL-27, a cytokine consisting of IL-27p28 and Epstein-Barr virus–induced gene 3 (EBI3), binds a membrane-bound heterodimeric receptor consisti...
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Asıl Yazarlar: | , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
American Society for Investigative Pathology
2011
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204191/ https://ncbi.nlm.nih.gov/pubmed/21925473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.08.001 |
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