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The Discovery of LOX-1, its Ligands and Clinical Significance
LOX-1 is an endothelial receptor for oxidized low-density lipoprotein (oxLDL), a key molecule in the pathogenesis of atherosclerosis.The basal expression of LOX-1 is low but highly induced under the influence of proinflammatory and prooxidative stimuli in vascular endothelial cells, smooth muscle ce...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer US
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204104/ https://ncbi.nlm.nih.gov/pubmed/21805404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-011-6324-6 |
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