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The tumor suppressor adenomatous polyposis coli controls the direction in which a cell extrudes from an epithelium

Despite high rates of cell death, epithelia maintain intact barriers by squeezing dying cells out using a process termed cell extrusion. Cells can extrude apically into the lumen or basally into the tissue the epithelium encases, depending on whether actin and myosin contract at the cell base or ape...

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Autors principals: Marshall, Thomas W., Lloyd, Isaac E., Delalande, Jean Marie, Näthke, Inke, Rosenblatt, Jody
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204059/
https://ncbi.nlm.nih.gov/pubmed/21900494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-05-0469
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