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Activating Transcription Factor 3 Deficiency Promotes Cardiac Hypertrophy, Dysfunction, and Fibrosis Induced by Pressure Overload

Activating transcription factor 3 (ATF3), which is encoded by an adaptive-response gene induced by various stimuli, plays an important role in the cardiovascular system. However, the effect of ATF3 on cardiac hypertrophy induced by a pathological stimulus has not been determined. Here, we investigat...

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Bibliographic Details
Main Authors: Zhou, Heng, Shen, Di-Fei, Bian, Zhou-Yan, Zong, Jing, Deng, Wei, Zhang, Yan, Guo, Yuan-Yuan, Li, Hongliang, Tang, Qi-Zhu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203896/
https://ncbi.nlm.nih.gov/pubmed/22053207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026744
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