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Contributions of Histone H3 Nucleosome Core Surface Mutations to Chromatin Structures, Silencing and DNA Repair

Histone H3 mutations in residues that cluster in a discrete region on the nucleosome surface around lysine 79 of H3 affect H3-K79 methylation, impair transcriptional silencing in subtelomeric chromatin, and reveal distinct contributions of histone H3 to various DNA-damage response and repair pathway...

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Main Authors: Fink, Michel, Thompson, Jeffrey S., Thoma, Fritz
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203891/
https://ncbi.nlm.nih.gov/pubmed/22053185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026210
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