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HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines
BACKGROUND: Hepatocyte Nuclear Factor 1α (HNF1α) is an atypical homeodomain-containing transcription factor that transactivates liver-specific genes including albumin, α-1-antitrypsin and α- and β-fibrinogen. Biallelic inactivating mutations of HNF1A have been frequently identified in hepatocellular...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203860/ https://ncbi.nlm.nih.gov/pubmed/21975049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-427 |
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