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High Throughput Screening of Small Molecule Libraries for Modifiers of Radiation Responses

PURPOSE: An unbiased approach of drug discovery through high-throughput screening (HTS) of libraries of chemically defined and bioactive small molecule compounds was used to identify modulators of radiation injury with an emphasis on radioprotectors and mitigators rather than radiosensitizers. Assay...

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Autors principals: Kim, Kwanghee, Damoiseaux, Robert, Norris, Andrew J., Rivina, Leena, Bradley, Kenneth, Jung, Michael E., Gatti, Richard A., Schiestl, Robert H., McBride, William H.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203687/
https://ncbi.nlm.nih.gov/pubmed/21401317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2011.560994
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