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A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis

The Wnt/β-catenin signaling pathway is a highly conserved pathway in organism evolution and regulates many biological processes. Aberrant activation of the Wnt/β-catenin signaling pathway is closely related to tumorigenesis. In order to identify potent small molecules to treat the over-activated Wnt...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Wei, Liu, Haiyang, Wang, Sheng, Hao, Xiaojiang, Li, Lin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203668/
https://ncbi.nlm.nih.gov/pubmed/21321609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.30
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