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Mutational analysis of the necdin gene in patients with congenital isolated hypogonadotropic hypogonadism
CONTEXT: Necdin activates GNRH gene expression and is fundamental for the development, migration, and axonal extension of murine GNRH neurons. In humans, necdin plays a potential role in the hypogonadotropic hypogonadism phenotype in patients with Prader–Willi syndrome. AIM: To investigate necdin ge...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203643/ https://ncbi.nlm.nih.gov/pubmed/21543378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-11-0199 |
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