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Misannotations of rRNA can now generate 90% false positive protein matches in metatranscriptomic studies

In the course of analyzing 9 522 746 pyrosequencing reads from 23 stations in the Southwestern Pacific and equatorial Atlantic oceans, it came to our attention that misannotations of rRNA as proteins is now so widespread that false positive matching of rRNA pyrosequencing reads to the National Cente...

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Detalles Bibliográficos
Main Authors: Tripp, H. James, Hewson, Ian, Boyarsky, Sam, Stuart, Joshua M., Zehr, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203614/
https://ncbi.nlm.nih.gov/pubmed/21771858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr576
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