Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

Immune-regulated pathways influence multiple aspects of cancer development. In this article we demonstrate that both macrophage abundance and T-cell abundance in breast cancer represent prognostic indicators for recurrence-free and overall survival. We provide evidence that response to chemotherapy...

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Detalhes bibliográficos
Main Authors: DeNardo, David G., Brennan, Donal J., Rexhepaj, Elton, Ruffell, Brian, Shiao, Stephen L., Madden, Stephen F., Gallagher, William M., Wadhwani, Nikhil, Keil, Scott D., Junaid, Sharfaa A., Rugo, Hope S., Hwang, E. Shelley, Jirström, Karin, West, Brian L., Coussens, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203524/
https://ncbi.nlm.nih.gov/pubmed/22039576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8274.CD-10-0028
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