Reprogramming efficiency and quality of induced Pluripotent Stem Cells (iPSCs) generated from muscle-derived fibroblasts of mdx mice at different ages

Induced pluripotent stem cells (iPSCs) hold promise as a potential treatment for Duchenne muscular dystrophy (DMD). To determine the impact of the donor’s age on reprogramming, we generated iPSCs from muscle-derived fibroblasts (MuFs) of mdx mice aged 6 weeks, 6 months, and 14 months. MuFs from 14-m...

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Detalhes bibliográficos
Main Authors: Wang, Bo, Miyagoe-Suzuki, Yuko, Yada, Erica, Ito, Naoki, Nishiyama, Takashi, Nakamura, Miho, Ono, Yusuke, Motohashi, Norio, Segawa, Makoto, Masuda, Satoru, Takeda, Shin'ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Muscular Dystrophy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203521/
https://ncbi.nlm.nih.gov/pubmed/22101343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1274
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