Chlamydia psittaci Genetic Variants Differ in Virulence by Modulation of Host Immunity

Background. Psittacosis is a zoonosis caused by Chlamydia psittaci and is characterized by severe pneumonia and systemic infection. We sought to determine the basis of the 1000-fold difference in lethal dose of 2 C. psittaci 6BC strains in mice. Methods. Genomes of the strains were sequenced. Mice w...

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Autori principali: Miyairi, Isao, Laxton, Jonathan D., Wang, Xiaofei, Obert, Caroline A., Arva Tatireddigari, Venkat R. R., van Rooijen, Nico, Hatch, Thomas P., Byrne, Gerald I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203387/
https://ncbi.nlm.nih.gov/pubmed/21791668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir333
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