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Quantitative utilization of prior biological knowledge in the Bayesian network modeling of gene expression data

BACKGROUND: Bayesian Network (BN) is a powerful approach to reconstructing genetic regulatory networks from gene expression data. However, expression data by itself suffers from high noise and lack of power. Incorporating prior biological knowledge can improve the performance. As each type of prior...

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Detalhes bibliográficos
Main Authors: Gao, Shouguo, Wang, Xujing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203352/
https://ncbi.nlm.nih.gov/pubmed/21884587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-359
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