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Multi-objective optimization of enzyme manipulations in metabolic networks considering resilience effects

BACKGROUND: Improving the synthesis rate of desired metabolites in metabolic systems is one of the main tasks in metabolic engineering. In the last decade, metabolic engineering approaches based on the mathematical optimization have been used extensively for the analysis and manipulation of metaboli...

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Detalhes bibliográficos
Main Authors: Wu, Wu-Hsiung, Wang, Feng-Sheng, Chang, Maw-Shang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203348/
https://ncbi.nlm.nih.gov/pubmed/21929795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-145
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