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The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.
Two foreign cloned genes--one encoding a tissue-specific protein and one encoding a constitutive enzyme--were introduced into mouse eggs by microinjection into a pronucleus shortly after fertilization. They were the adult human genomic beta-globin gene and the thymidine kinase (TK; ATP:thymidine 5&#...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1981
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320323/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6272287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.8.5016 |
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