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Histone Deacetylase 8 Is Required for Centrosome Cohesion and Influenza A Virus Entry
Influenza A virus (IAV) enters host cells by endocytosis followed by acid-activated penetration from late endosomes (LEs). Using siRNA silencing, we found that histone deacetylase 8 (HDAC8), a cytoplasmic enzyme, efficiently promoted productive entry of IAV into tissue culture cells, whereas HDAC1 s...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203190/ https://ncbi.nlm.nih.gov/pubmed/22046129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002316 |
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