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The Fission Yeast RNA Binding Protein Mmi1 Regulates Meiotic Genes by Controlling Intron Specific Splicing and Polyadenylation Coupled RNA Turnover

The polyA tails of mRNAs are monitored by the exosome as a quality control mechanism. We find that fission yeast, Schizosaccharomyces pombe, adopts this RNA quality control mechanism to regulate a group of 30 or more meiotic genes at the level of both splicing and RNA turnover. In vegetative cells t...

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Autors principals: Chen, Huei-Mei, Futcher, Bruce, Leatherwood, Janet
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203177/
https://ncbi.nlm.nih.gov/pubmed/22046364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026804
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