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Evidence for Retrogene Origins of the Prion Gene Family

The evolutionary origin of prion genes, only known to exist in the vertebrate lineage, had remained elusive until recently. Following a lead from interactome investigations of the murine prion protein, our previous bioinformatic analyses revealed the evolutionary descent of prion genes from an ances...

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Bibliographic Details
Main Authors: Ehsani, Sepehr, Tao, Renzhu, Pocanschi, Cosmin L., Ren, Hezhen, Harrison, Paul M., Schmitt-Ulms, Gerold
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203146/
https://ncbi.nlm.nih.gov/pubmed/22046361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026800
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