Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study

BACKGROUND: During inflammation, immune cells accumulate in damaged areas and release pro-inflammatory cytokines and neurotrophins. Brain-derived neurotrophic factor (BDNF) plays a neuromodulatory role in spinal cord dorsal horn via the post-synaptic tyrosine protein kinase B (trkB) receptor to faci...

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Detalhes bibliográficos
Main Authors: Lin, Ya-Tin, Ro, Long-Sun, Wang, Hung-Li, Chen, Jin-Chung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203068/
https://ncbi.nlm.nih.gov/pubmed/21958434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-126
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