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Positive cooperativity of the estrogen receptor.

The equilibrium [3H]estradiol binding by the partially purified estrogen receptor from calf uteri was measured at 25 degrees C. The Scatchard plot of the binding data showed a convex curve characteristic of positive cooperativity and a Hill coefficient of 1.58 +/- 0.21, at receptor concentrations of...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Notides, A C, Lerner, N, Hamilton, D E
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320297/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6946439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.8.4926
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