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Role of the Intrarenal Renin-Angiotensin-Aldosterone System in Chronic Kidney Disease

The existence of local or tissue-based renin-angiotensin-aldosterone systems (RAAS) is well documented and has been implicated as a key player in the pathogenesis of cardiovascular and renal diseases. The kidney contains all elements of the RAAS, and intrarenal formation of angiotensin II not only c...

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Autori principali: Siragy, Helmy M., Carey, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202956/
https://ncbi.nlm.nih.gov/pubmed/20484892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000313363
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